Endocrine Abstracts

Tuberculosis affecting the pituitary gland is a rare phenomenon and is usually the result of haematological spread from another site. Only 0.9% of cases of TB in the UK, in 2012, showed any CNS involvement, excluding meningitis1. The clinical presentation of pituitary TB, range of hormonal dysfunction and radiological features can vary, making it hard to identify the condition. We report two clinical cases seen in our department.Case 1: A 48-y...

A 27-year-old female presented with severe lethargy; she was found to have hypercalcaemia with corrected calcium of 3.27 mmol/L and biochemistry suggestive of primary hyperparathyroidism (PTH–64.7 umol/L [1.5–7.5 pmol/L]). She had no notable family history of endocrinopathies or malignancies. Imaging suggested two possible parathyroid adenomas at the upper and lower poles of the posterior right lobe of the thyroid and she was referred for surgical intervention. Intra...

Adrenal haemorrhage is a relatively rare phenomenon which can often present non-specifically. In the case of bilateral haemorrhages, if unrecognised the endocrine sequelae may prove to be fatal. These three cases highlight very different clinical presentations of this important condition.Case 1: A 74-year-old male was admitted following a fall and fractured neck of femur. His post-operative recovery was complicated by acute myocardial infarction, pneumon...

Background: Cranial diabetes inspidus (DI) may be familial or acquired. Traumatic brain injury is an important cause of acquired cranial DI, occurring in up to 22% of patients with moderate or severe head injuries1.Case 1: A 20-year-old male was admitted following a road traffic accident (RTA) with polytrauma including several skull fractures, subdural haematoma, and pneumocephalus. The following day, he developed polyuria and polydipsia. Bioc...

Introduction: Primary hyperparathyroidism (PHPT) is a commonly encountered endocrine pathology. Asymptomatic renal stones have been reported in 7-22% of patients. NICE guideline (NG132) published in May 2019 on PHPT recommends renal US in all patients. The value of renal ultrasound for all patients with PHPT has been debated. This audit aims to compare local practice to NICE guideline (NG132) and to see if a tailored approach for renal ultrasound would be safe, practical and e...